Your safety is our first priority. Learn more about key medication details, possible side effects, warnings, and other important information about semaglutide microdosing below.
Prescribing Information
Semaglutide microdosing is a compounded, provider-determined lower-dose approach that may be prescribed when clinically appropriate. It is not a separately FDA-approved product or dosing regimen. Compounded semaglutide is not FDA-approved as a finished drug product and is not the same as Wegovy® or Ozempic®.
Black Box Warning
There is no FDA-approved prescribing label specific to compounded semaglutide microdosing. However, FDA-approved semaglutide products carry a boxed warning for the risk of thyroid C-cell tumors. Do not use semaglutide if you or your family have a history of medullary thyroid carcinoma, or MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2, or MEN 2.
Common Side Effects
Common or possible side effects may include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain
- Heartburn or indigestion
- Decreased appetite
- Fatigue
- Headache
- Dizziness
- Injection-site reactions
Important Safety Information
Do not use semaglutide if you have a known allergy to semaglutide or any ingredient in the medication, have a personal or family history of MTC, or have MEN 2.
Tell your provider if you have or have had pancreatitis, gallbladder disease, kidney disease, diabetic retinopathy, severe stomach or digestion problems, diabetes, depression, suicidal thoughts, or are pregnant, planning pregnancy, or breastfeeding.
Semaglutide may increase the risk of pancreatitis, gallbladder problems, dehydration, kidney injury, severe gastrointestinal reactions, low blood sugar when used with certain diabetes medications, allergic reactions, increased heart rate, and worsening diabetic retinopathy in certain patients. It may slow stomach emptying and affect oral-medication absorption.
Compounded products may have different concentrations and syringe instructions. Confirm the dose in milligrams, milliliters, and syringe units before every injection. Dosing errors can cause severe nausea, vomiting, dehydration, and low blood sugar.
Seek urgent medical help for severe abdominal pain, swelling of the face or throat, trouble breathing, severe vomiting, fainting, symptoms of dehydration, or signs of an allergic reaction.
To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.
