Your safety is our first priority. Learn more about key medication details, possible side effects, warnings, and other important information about vitamin c injection below.
Prescribing Information
Vitamin C injection contains ascorbic acid and may be FDA-approved for limited deficiency-related use or may be compounded for an off-label provider-determined purpose. Safety depends on dose, route, kidney function, G6PD status, iron-storage conditions, and the exact formulation.
Black Box Warning
Vitamin C injection does not have a boxed warning. High-dose or prolonged injectable ascorbic acid can cause serious kidney injury from oxalate, hemolysis in patients with G6PD deficiency, and interference with certain laboratory tests.
Common Side Effects
Common or possible side effects may include:
- Injection or infusion-site pain
- Swelling
- Nausea
- Flushing
- Headache
- Dizziness
- Abdominal discomfort
- Fatigue
Important Safety Information
Tell your provider if you have kidney impairment, a history of oxalate kidney stones, G6PD deficiency, hemochromatosis or another iron-overload condition, diabetes, pregnancy, or breastfeeding. Screening may be required before higher-dose treatment.
Ascorbic acid can interfere with some blood and urine tests, including certain glucose measurements. Tell healthcare professionals and laboratories when you have recently received injectable vitamin C.
Stop treatment and contact your provider for reduced urination, severe flank pain, dark urine, yellowing of the skin or eyes, severe weakness, or persistent vomiting.
Seek urgent medical help for trouble breathing, fainting, severe allergic symptoms, or signs of hemolysis or acute kidney injury.
To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

