Targets hormone-driven skin pathways
Spironolactone has anti-androgen activity. Topical formulations aim to bring that activity directly to areas of the skin affected by androgen-related breakouts.
From $119.00Current price is: $119.00. $169.00 Original price was: $169.00./mo.
A provider-guided compounded topical spironolactone option that may be considered for eligible patients with acne, oiliness, or other androgen-related skin concerns. The topical formulation is not FDA-approved as a finished drug product and should be used with ingredient-specific pregnancy and medication precautions.
A provider-guided compounded topical spironolactone option that may be considered for eligible patients with acne, oiliness, or other androgen-related skin concerns. The topical formulation is not FDA-approved as a finished drug product and should be used with ingredient-specific pregnancy and medication precautions.
Spironolactone has anti-androgen activity. Topical formulations aim to bring that activity directly to areas of the skin affected by androgen-related breakouts.
Clinical studies of topical spironolactone have reported reductions in acne lesion counts in some patients.
Unlike oral spironolactone, the topical formulation is applied directly to the prescribed skin areas as part of a personalized skincare routine.
Treatment Options
All treatments include:
All treatments include:
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It is a topical formulation of spironolactone used in some compounded dermatology programs for androgen-related skin concerns such as acne.
Spironolactone has anti-androgen activity, and the topical approach is intended to deliver treatment directly to the skin.
Yes. Clinical studies, including research involving 5% topical spironolactone, have reported reductions in acne lesion counts.
No. A compounded topical spironolactone formulation is not an FDA-approved acne medication.
Follow the exact amount, frequency and application instructions provided by your clinician and dispensing pharmacy because compounded formulations can differ.
Topical spironolactone has been studied in acne patients, but whether it is appropriate should be determined individually by the prescribing clinician.
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“Ms. Gonzalez was great! She listened to my needs and provided details of the meds and any issues that arise.”
“The provider was knowledgeable and helpful. She answered all my questions and made me feel very comfortable.”
“The questions are to the point and easy to navigate. They are quick to respond and keep me updated on my prescription.”
“My experience is very positive. They have been attentive and provided me with the resources to be successful.”
“Everything felt simple from the start. The provider was kind, informative, and made me feel comfortable asking questions.”
“The support has been great. I never felt rushed, and my questions were answered in a way that actually made sense.”
“The provider listened to my concerns and gave clear guidance. It felt personal, not like a one-size-fits-all program.”
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“Losing weight without a crazy diet or endless cardio felt like magic. I feel so much better.”
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“I was ready to give up. The metabolic support has been a game changer for me.”
“The doctors and staff have been professional and prompt with every question. I feel like I am in great hands.”

“My clinician was kind and informative, with a clear explanation of expectations and future follow-ups.”
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